Institute of Snake Venom and Snakebite, Southern Anhui Medical College
Inisetiute Suesuega a Wuhu City, Anhui Province
O suʻesuʻega i gata oona ma manuʻa gata a Southern Anhui Medical College na amata i le ogatotonu o 1970s, ma sa avea ma sui o le Anhui Provincial Snake Wound Treatment Cooperation Group i lena taimi.O se tasi o faʻalapotopotoga muamua na faia suʻesuʻega faʻavae ma faʻaogaina i luga o gata oona i Saina.
igoa Saina
Institute of Snake Venom and Snakebite, Southern Anhui Medical College
nofoaga
Itumalo o Anhui
ituaiga
aoga fa'au'u
mea faitino
Oona gata ma Manu'a gata
Su'esu'ega taunu'uga a le Inisetiute
Folasaga i le Inisetiute
O suʻesuʻega i gata oona ma manuʻa gata a Southern Anhui Medical College na amata i le ogatotonu o 1970s, ma sa avea ma sui o le Anhui Provincial Snake Wound Treatment Cooperation Group i lena taimi.I le 1984, i lalo o le taʻitaʻiga a Polofesa Wen Shangwu, o le faʻatonu o le matagaluega o aʻoaʻoga ma suʻesuʻega o uluai tamaiti aʻoga mamaʻi, na faʻatūina le Snake Poison and Snakebite Research Office, o se tasi lea o faʻalapotopotoga muamua e faia suʻesuʻega faʻavae ma faʻaaogaina. i gata oona i Saina.I le 2007, o le Snake Poison and Snakebite Research Office na toe faʻaigoaina le Snake Poison Research Institute o Southern Anhui Medical College, ma o le faatonu o loʻo iai nei o Polofesa Zhang Genbao.I le 30 tausaga talu ai, o le autu ma le faʻaaogaina o suʻesuʻega na ausia o toxins gata oona i le itu i saute o Anhui ua faia ai sao taua i le puipuia ma le puleaina o manuʻa gata ma le faʻaogaina o punaoa oona gata i Saina;O gata oona autu i le itu i saute o Anhui o Agkistrodon acutus (Agkistrodon acutus), Agkistrodon acutus, Cobra, Green Bamboo Leaf Snake, Chromium Iron Head ma Bungarus multicinctus, aemaise Agkistrodon acutus, lea e matua afaina ai le soifua maloloina ma le ola o tagata mauga.O suʻesuʻega ua faʻaalia ai o nei gata oona e masani lava ona maua ai le toto toto o toxins ma neurotoxins, lea e mafai ona mafua ai ona mafatia tagata mamaʻi mai le faʻasalalauina o le intravascular coagulation (DIC) ma le toto lona lua, faʻateʻia, tele o totoga faaletonu ma isi taunuuga ogaoga;E ala i se suʻesuʻega faʻasolosolo i luga o le toto oona o le oona o Agkistrodon acutus (Agkistrodon acutus) i le itu i saute o Anhui, na maua ai o le DIC e fesootaʻi ma le gata gata o se tasi lea o faʻailoga masani o le vave ona oona, ma e ese mai le DIC faʻaalia i tu ma aga masani. vaaiga.O le mea lea, o le manatu o le "DIC pei" syndrome i tagata mamaʻi na utia e Agkistrodon acutus na muamua faʻatulagaina i Saina (1988), Na iloa foi o le thrombin pei o le enzyme (TLE) ma le fibrinolytic enzyme (FE) o loʻo i totonu o le oona o Agkistrodon acutus sa mafuaaga autu o lenei "DIC pei" (1992).E taua tele lenei mea e faʻamalamalama ai uiga o suiga o le toto i tagata mamaʻi ma le Agkistrodon acutus, ma tuʻuina atu foi se faʻavae faʻavae mo le faʻaaogaina o vailaʻau faʻapitoa e togafitia ai lenei faʻalavelave.I le suʻesuʻega i luga o le faiga o le tafe toto na mafua mai i le Agkistrodon acutus venom, na maua ai foi o lenei gata oona na i ai se aafiaga i vaega tetele e tolu o le hemostatic system (coagulation factors, platelets and blood vessels), lea e saʻo ai le haemotoxin. afaina ai le permeability o capillaries.I le taimi lava e tasi, na aʻoaʻoina ai o le ogaoga o le toto na mafua mai i le Agkistrodon acutus venom poisoning ma le faigata o le fulafula o vae manua e faʻaitiitia e fesoʻotaʻi ma le poloka o le faʻaopoopoga o le lymphatic o mea faʻapipiʻi i totonu o le thoracic duct ma le leaga o le tafe o le lymphatic.O nei fa'avae su'esu'ega fa'avae ma fa'aaogaina ua faia se sao taua i le galulue fa'atasi ma le Qimen Snakebite Research Institute i le fa'atulagaina lelei o le fuafuaga mo togafitiga mo le gata gata ma fa'amautinoaina le saogalemu o tagata mama'i gata, ma ua ausia a'afiaga fa'aagafesootai taua.O taunu'uga o su'esu'ega ua manumalo fa'asolosolo i le Fa'ailoga Fa'aSaienisi ma Tekinolosi Achievement a le Itumalo o Anhui, le Fa'ailoga o le Saienisi ma Tekonolosi Alualu i Luma o Anhui Province (1993), ma le (A) tulaga Fa'asaienisi ma Tekinolosi Achievement Collective Award a le Matagaluega o le Soifua Maloloina (1991);I le 1989, na galulue faatasi ai ma le Wuhan Institute of Biological Products e atiaʻe se antibody monoclonal e faasaga i le thrombin e pei o le enzyme o le Agkistrodon acutus venom, lea na muamua manuia i Saina;I le 1996, o loʻo tuʻufaʻatasia ma atinaʻe oloa thrombin (YWYZZ 1996 Nu. 118004, pateni CN1141951A) ma le Inisetiute o Mea Faʻaola ma Fualaau Faʻasaina o Jinan Military Region.
sailiiliga sailiiliga
I tausaga talu ai nei, o le fale suʻesuʻe ua vavae ese ma faʻamamāina le tele o mea olaola mai mea leaga o Agkistrodon acutus, Agkistrodon halys ma Cobra i le itu i saute o Anhui, e pei o enzymes anti hypercoagulable state, protein C activators (PCA).O suʻesuʻega faʻataʻitaʻiga ua faʻamaonia ai o nei mea aoga e mafai ona aʻafia ai le faʻagasologa o le coagulation, aʻafia ai le platelet adhesion, faʻapipiʻiina ma puipuia le gaioiga o sela endothelial vascular, ma maua ai le maualuga ma le maualalo o le toxicity anticoagulation ma thrombolytic aafiaga, E taua tele lenei mo le puipuia ma togafitiga. o faʻamaʻi thrombotic ma le faʻaleleia atili o le toto toto;I le taimi lava e tasi, na maua ai foi o le PCA mai le gata oona o loʻo i ai le aafiaga faʻapitoa o le fasiotia o sela K562 leukemia ma faʻalavelaveina le metastasis o sela o le kanesa.O lona fa'amoemoega fa'atatau ile falema'i e matua lautele lava.O le ofisa suʻesuʻe na faʻasolosolo faʻataunuʻuina ma faʻamaeʻaina le tele o galuega suʻesuʻe, e pei o le "Mechanism of DIC na mafua mai i le Agkistrodon acutus venom", "Suʻesuʻega i le faiga o le tafe toto e mafua mai i le Agkistrodon acutus venom i manu", "Diagnosis o le gata ma le eseesega o suʻesuʻega o lona aiga gata e ala i le enzyme labeling method”, faatupeina e le National Natural Science Foundation, le Matagaluega o le Soifua Maloloina, Matagaluega o le Soifua Maloloina ma le Matagaluega o Aoga a le Anhui Province;I le taimi nei, o poloketi o loʻo i lalo o le atinaʻe e aofia ai: "Suʻesuʻega i le Hemorrhagic Anticoagulant Protein of Agkistrodon acutus", "Suʻesuʻega ile Molecular Mechanism of the Effect of PCA from Agkistrodon halys Pallas Venom on Vascular Endothelial Function", "Suʻesuʻega ile Molecular Biology of PCA mai le Agkistrodon acutus Venom e faasaga i Tumor Cells", ma le vavaeeseina ma le faʻamamāina o le Nerve Analgesic Components mai le Cobra Venom.
O le inisitituti suʻesuʻega oona gata a South Anhui Medical College o loʻo i ai tulaga lelei faʻavae, meafaigaluega suʻesuʻe atoatoa, faʻatulagaina au suʻesuʻe talafeagai, ma faʻaauau le alualu i luma i metotia suʻesuʻe ma auala faʻapitoa.O loʻo faʻamoemoeina e faia ni taunuʻuga fou i suʻesuʻega faʻasaienisi, aʻoaʻoga a tagata faigaluega, ma isi mea. O punaoa oona gata i le itu i saute o Anhui e matua mauoa ma taua.O le falema'i oona gata ose vaila'au fa'atasi ai ma aia tatau tau meatotino i Saina.O suʻesuʻega i luga o le faʻavae ma le faʻaogaina o le gata oona ma ona vaega e taua tele i le atinaʻeina o punaoa oona gata mauoa i le itu i saute o Anhui ma le falemaʻi.
Taimi meli: Nov-11-2022