O le gata oona e tele vaega olaola, e aofia ai le protease ma le polypeptide
E tusa ma le 90%~95% o le mamafa mago o gata oona [l
Faatasi ai ma le faʻaauauina o le atinaʻeina o tekonolosi, o le tele o mea ola faʻamalosi i le gata gata e faasolosolo malie
Ua tuueseeseina ma faamamaina, ma ua faia e tagata
Faia suʻesuʻega loloto i luga ma le faʻamoemoe e faʻaogaina vailaʻau aoga aoga i le gata oona i tagata
I le togafitia o faʻamaʻi tutusa.I le taimi nei, o mea aoga o vailaʻau aoga o loʻo i totonu o le gata oona
Ole su'esu'ega ole vaila'au ma le fa'aogaina ole falema'i e fa'atatau ile antithrombotic, hemostatic ma le hypoglycemic
O'omiga, fa'ama'i o le kanesa ma fa'ama'i tiga.
L vaila'au fa'ama'i
O le gata oona protease faʻatasi ai ma aʻafiaga anti-thrombotic ma thrombolytic e masani ona aofia ai Ancelor
Enzyme (hoe crod), batmxobin, defibrase (de coerase) ma Agkistrodon acutus
Enzyme (acutobin).O mea muamua e tolu o le snaI [e venom
Thmmbin pei o enzynles, s Ⅷ.E), sVTLE o serine protease, tutusa ma
E iai le arginine esterase ma le amidase gaioiga - 1. Snake venom thrombin-like enzyme
E galue i luga o fibrinogen e faʻasaʻo ai fibrinogen A poʻo B, faʻapea
E mafai ona coagulate le polymerization o fibrin monomer ulu ma siʻusiʻu, aua e faʻaalia le thrombin
Galuega ma e ta'ua o le thrombin-pei.I le taimi lava e tasi, e le mafai ona maua le enzyme e pei o le thrombin pei o le gata i tagata
Fa'agaoioia le mea e fa'a'a'ai ai x Ⅲ in vivo, ma o le fibrin monomer e maua mai i lona fa'asusu e mafai.
Polymerization o le ulu ma le si'usi'u, ae le mafai ona maua le laina faʻalava o le itu, lea e faigofie ona faʻaleagaina e le natura reticuloendothelial system.
Ole maualuga ole plasma fibrinogen ua fa'aitiitia ona ole phagocytosis po'o le fa'aleagaina e le fibrinolytic system
O loʻo i totonu o se tulaga fibrinolytic lelei, o lea e faʻaalia ai le faʻamaʻi ma le atuatuvale i le tino
Fibrillation H1.Agkistrodon acutus enzyme e a'afia i le fibrinolytic enzyme, o le fibrinolytic
O le faapuupuuga o le enzyme [Erin (ogen) ol "icenzyme, FLE] e mafai ona vaevaeina i le filifili tasi.
Zinc metalloproteinase ma filifili tasi pe lua filifili serine protease, o le tele o fuamoa u'amea zinc
Enzyme paepae.Snake venom fibrinolytic enzyme e le manaʻomia le faʻagaoioia o le activator, ma e mafai ona tipi saʻo alava
O le porotini (protogen) e gaosia ai le hemofibrin, o lea o le a le mafua ai le tuufaatasiga "J.
Mai le oona o Agkistrodon halys (eg sek, № r [md ∞ to, vaa) i Meleisia
O le ankylose tu'ufua o le mea muamua lea na fa'aaogaina i togafitiga fa'afoma'i o fa'ama'i thrombotic
SVTLE fualaau.6 J. Ina ua mavae le atiina ae o Ancelose, sa suesueina muamua e le tele o atunuu
E talitonu tagata suʻesuʻe o le sV'11E o le vailaʻau sili ona lelei mo le togafitia o faʻamaʻi thrombotic,
I le faʻaopoopoga i le faʻaaogaina mo le togafitiga o le thrombosis peripheral, e mafai foi ona faʻaaogaina mo togafitiga o le loloto o le venous thrombosis ma le ogatotonu o le venous thrombosis.
Pulse thrombosis e iai foʻi aʻafiaga faʻamalolo "J.E oo atu i le 1990s, tele atunuu ma itulagi
Qu Du e matua fiafia lava i le togafitiga o le maʻi o le cerebral ischemia ma le stroke ma le aclase, ma
Poloketi fa'aputugatupe: Poloketi Fa'ato'aga a Tupulaga Talavou Fa'afoma'i Fa'afoma'i ma Tekinolosi (13QNP068);O le autau atoa “12
5 “poloketi su'esu'ega fa'afoma'i lautele (cwslJ280);Chengdu Military Region "12th Five-Year Fuafuaga" Suʻesuʻega Faʻafomaʻi
Poloketi autu (B12026);Poloketi suʻesuʻega faʻafomaʻi lautele a Chengdu Military Region i le taimi o le 12th Five-Year Plan
(C12062)
Vaega a le Tusitala: 650032 Kunming, Chengdu Military Region Center mo Faʻamaʻi Pulea ma Puipuiga (Zhang Zhixiao,
Hu Tingsong, Cui Qinghua, Zheng Ying, Fan Quanshui);Pathogens, A'oga Fa'afoma'i Autu, Kolisi Fa'afomai a Youjiang mo Nationalities
Biology ma Immunology A'oa'oga ma Su'esu'ega Ofisa (Xie Zhenfeng)
Tusitala tutusa: Fan Quanshui, I-meli: fqsl68@126 ．com
E tele ni su'esu'ega fa'apitoa tau falema'i na fa'atinoina.Fa'ailoga ole su'esu'ega ole fa'aaogāina ole vaila'au muamua
E le gata i lea, e mafai ona faʻaaogaina le Ancelose i togafitiga faʻafomaʻi o tagata mamaʻi maʻi maʻi ischemic stroke i le amataga
E fa'aalia lelei le a'afiaga.A maeʻa lena, faʻatasi ai ma le tele-tele randomized double-blind, placebo pair
E tusa ai ma le faʻataʻitaʻiga falemaʻi, o ia, ma isi. Mo 2613 mataupu o maʻi
O faʻamaʻi togafitiga faʻamaʻi o tagata mamaʻi e maua i feusuaiga ischemic stroke na faʻamaonia ai o tagata gasegase i le vaega cloroxobin
O le fua faatatau o le ola na matua faateleina, ae o le tulaga lamatia o le toto toto na faateleina foi.Pe 'a uma lena
O le faʻataʻitaʻiga a le falemaʻi o le 1222 tagata maʻi na maua i le maʻi o le ischemic stroke na faʻamaonia ai ina ua maeʻa le 3 itula
E le fautuaina le Ancelose mo togafitiga.1…. O le Iunaite Setete ma Kanata na lomia i le 2009
500 taia e aofia ai le 12 atunuu ma itulagi e aofia ai Kanata ma Ausetalia
mafatia mai
Taimi meli: Feb-26-2023